The avian flu outbreak that has led to the slaughter of millions of birds at U.S. poultry farms and driven up the price of eggs struck the Crescent Duck Farm this week, leading federal officials to order the destruction of the operation’s entire flock.

The highly infectious H5N1 strain has caused outbreaks across the country. Now, Long Island’s last duck farm must kill its entire flock and may go out of business, its owner said.

The owner of the Crescent Duck Farm in Aquebogue, N.Y., has been forced to euthanize its flock of more than 100,000 ducks due to positive bird flu tests.