Keys, the No. 6 seed, was easily beaten in straight sets by 104th-ranked Laura Siegemund of Germany, while Sabalenka fought off a partisan crowd to beat Britain's Emma Raducanu.

Keys’ exit left just one of the top six women in the bracket before the end of Week 1: No. 1 Aryna Sabalenka, who stuck around by claiming the last five games and defeating 2021 U.S. Open champion Emma Raducanu of Britain 7-6 (6),

Naomi Osaka’s quest to get past the third round at Wimbledon for the first time in her career ended on Friday with a three-set loss to Anastasia Pavlyuchenkova.

Naomi Osaka might be more comfortable on grass courts these days but she will once again leave Wimbledon in the third round after a 3-6, 6-4, 6-4 loss to Anastasia Pavlyuchenkova

Six of Osaka's last seven defeats have been in three sets, with the four-time Grand Slam champion closer than ever to a return to form.