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Houston Texans, San Francisco 49ers

Texans vs. 49ers 2025 Prediction, Odds, Picks - Oct 26

The Houston Texans (2-4) are considered favorites (-1.5) according to the oddsmakers ahead of their game versus the San Francisco 49ers (5-2) on October 26, 2025, starting at 1 p.m. ET, airing on FOX.

USA TODAY Touchdown Wire on MSN · 3h

49ers vs. Texans picks: Who do experts predict will win Week 8 matchup?

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Texans vs. 49ers prediction, pick, odds for Sunday's NFL Week 8 game - 10/26/2025

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How to watch the 49ers vs. Texans on Sunday

Christian McCaffrey was named the NFC player of the week for his performance against Atlanta on Sunday Night Football, rushing for 129 yards and a pair of touchdowns, and adding 72 receiving yards.

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NFL prop bets Week 8 2025: Texans vs. 49ers

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Statistical Breakdown: How Texans and 49ers stack up before Week 8's showdown

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49ers vs. Texans: Where to watch NFL Week 8, betting odds, promos, score prediction for Mac Jones vs CJ Stroud

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

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Tennessee Titans vs. Indianapolis Colts injury report | Week 8 2025

Take a look at the injury report for the Tennessee Titans (1-6), which has 14 players listed (including Tony Pollard), as the Titans prepare for their matchup versus the Indianapolis Colts (6-1) at Lucas Oil Stadium,

NFL Monday Night Football prop bets Week 8 2025: Chiefs vs. Commanders

The Kansas City Chiefs (4-3) are listed as double-digit favorites (-11.5) on Monday, October 27, 2025 against the Washington Commanders (3-4). This contest has an over/under of 48. Get game prop insights to parlay below in this article,