Study provides a portrait of wild-type AAV infection in the liver with an identification of molecular forms, viral genotypes, viral integrations, and helper virus relationship and with AAV insertions ...

In a recent review published in Signal Transduction and Targeted Therapy, researchers presented recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases. Study: ...

The efficacy of adeno-associated virus (AAV)-mediated gene therapy for the inner ear is fundamentally constrained by the natural tropism of viral vectors, which often lack the precision and efficiency ...

The U.S. Food and Drug Administration today approved Otarmeni (lunsotogene parvec-cwha), the first-ever dual adeno-associated virus (AAV) vector-based gene therapy. Otarmeni is indicated for the ...

Four patients with infantile-onset Pompe’s disease received a single intravenous injection of an adeno-associated virus serotype 9 vector carrying codon-optimized complementary DNA encoding human acid ...

AMSBIO announce a new range of ready-to-use adeno-associated virus (AAV) biosensor products. These viruses encode your chosen biosensor, either calcium or glutamate sensor and are ready for in vivo ...

Developed by American Biotechnology company Regeneron, Otarmeni has been approved for the treatment of pediatric and adult patients with severe-to-profound and profound sensorineural hearing loss. The ...

Canine adenoviruses, particularly type 1 (CAdV-1), are well recognised as the primary aetiological agents of infectious canine hepatitis (ICH), a severe disease that continues to present significant ...

The customizable platform used AAVs to deliver genetic cargo that induced the production of three anti-inflammatory cytokines ...

Adenovirus isn’t as well-known as flu or COVID, but it’s one of the most common viruses people catch — especially in childhood. In fact, most people will have been infected at least once before the ...