Simon et al reviewed the skeletal consequences of discontinuing HT and the specific treatment options for these women. [12] This analysis included 11 RCTs that reported data on BMD changes during and ...

Long-term treatment with a bisphosphonate degrades fracture-resistance–toughening mechanisms that contribute to healthy bone, setting the stage for the rare but catastrophic risk of patients ...

Please provide your email address to receive an email when new articles are posted on . Despite potential side effects, bisphosphonate therapy may benefit postmenopausal women with osteoporosis by ...

The FDA analyses looked at a composite end point of all fractures, both vertebral and nonvertebral, and showed little benefit of continued bisphosphonate treatment beyond 5 years. The original ...

About a year was determined to be the minimal timing of bisphosphonate therapy for postmenopausal women with osteoporosis to reap a benefit, according to a meta-analysis. Looking at 10 randomized ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) seemed to neutralize the protective benefit of a certain bisphosphonate, according to a post-hoc analysis of a randomized controlled trial. Among over ...

Studies show conflicting results regarding the possible excess risk of atypical fractures of the femoral shaft associated with bisphosphonate use. In Sweden, 12,777 women 55 years of age or older ...

Long-term use of osteoporosis drugs seems to change bones in a way that could lead to unusual leg fractures, according to two reports presented at a meeting of orthopedic surgeons. Doctors have ...

Development of an Actionable Framework to Address Cancer Care Disparities in Medically Underserved Populations in the United States: Expert Roundtable Recommendations We conducted a retrospective ...

Directing Surgical Quality Improvement Initiatives: Comparison of Perioperative Mortality and Long-Term Survival for Cancer Surgery Osteonecrosis of the jaws (ONJ) was initially described in 2001 in ...