The promise of adoptive T-cell therapies—immunotherapy in which T cells are collected from a patient, enhanced, and reinfused—is growing, especially against blood cancers. However, a better ...

T cells experience different mechanical signals in different tissues. Researchers have engineered a tissue-mimicking hydrogel model to show that more elastic tissues induce T cells to become ...

The findings are reported in Nature Biomedical Engineering. Mechanical resistance comes in the form of "stiffness," a tissue's (or any material's) resistance to instantaneous deformation, and ...

Vertebrate skeletal tissues exhibit remarkable diversity in both their mechanical properties and evolutionary adaptations. These tissues are finely tuned composite materials where a combination of ...

(Boston) — The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the ...