Researchers were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction. Although in the early stages, the research ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers from the University of Pittsburgh and the University of Chicago were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Mutations in a calcium ion channel anoctamin 5 (ANO5), commonly found in muscle cells, cause the debilitating disease called limb girdle muscular dystrophy 2L (LGMD2L). Characterized by progressive ...

IT has been postulated that calcium ions act as the link between depolarization and contraction in cardiac 1 and skeletal muscle 2. This hypothesis is based on the results of experiments relating the ...

One of the most underrated minerals, calcium plays a huge part in many of the body’s biological processes. Best known for its role in bone and dental health, it’s also involved in muscle contraction, ...

THERE is abundant evidence that the sarcoplasmic reticulum (SR) of skeletal muscle plays an important part in excitation–contraction coupling and in relaxation of muscle fibres 1. It is usually ...

Muscles move our bodies. To do so, they contract, which then generates movement. Share on Pinterest Muscles use energy from our food to produce movement. Muscles allow us to consciously move our limbs ...