Thanks in part to the revolution cell therapy brought to treating blood cancers, the modality is now showing promise in some ...

CAR T cell therapy is moving beyond cancer, with emerging applications in autoimmune disease, infections, transplantation and ...

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific ...

Allogene Therapeutics stock is trying to create CAR-T treatments using cells from healthy donors. Here's what investors need ...

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is a standard treatment for relapsed or refractory B-cell non-Hodgkin lymphomas. Long-term results and curative potential remain uncertain. We ...

A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult ...

Beyond the potential clinical application, the study sheds new light on T cell biology and how cells are directed towards specific lineages.

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block ...

Once best known for treating blood cancers, CAR-T therapy is now being redesigned for solid tumors, autoimmune disease, and chronic viral infections, but the review shows that safety, persistence, and ...

HLA sensitization poses a major challenge to kidney transplantation for patients with end-stage kidney disease, especially for highly sensitized candidates. Attempts at antibody elimination ...