The burden of chronic pain. Source: GoodIdeas / Shutterstock Nerve sensitization often contributes to chronic pain states, such as back pain, migraines, and irritable bowel. Sensitization is an ...

Central sensitization describes the process by which neurons in the central nervous system become hyperresponsive following persistent or intense noxious input. This phenomenon relies on synaptic ...

Please provide your email address to receive an email when new articles are posted on . Central sensitization may be an important underlying factor that complicates the treatment of chronic pain and ...

Findings suggest that including slowly repeated evoked pain (SREP) in quantitative sensory testing protocols may enhance assessments of altered pain modulation in different pain conditions. Study ...

ORLANDO — Patients completing an outpatient interdisciplinary chronic pain rehabilitation program (iCPRP) at the Cleveland Clinic have significantly reduced self-reported central sensitization (CS) ...

Despite extensive research, the pathogenesis of pain in fibromyalgia syndrome is incompletely understood. Fibromyalgia pain is consistently felt in deep tissues including ligaments, joints and muscles ...

Gabapentin is a gamma-aminobutyric acid derivative, and was approved for the treatment of neuropathic pain by the U.S. Food and Drug Administration in 2002. However, little evidence is available on ...

In both traditional acupuncture theory and modern medical experience, acupoints are central to therapeutic outcomes, yet their biological nature has remained controversial. Conventional models assume ...

Hip Bursitis Patients with greater trochanteric pain syndrome may have altered conditioned pain modulation, as well as a high number of pain locations associated with negative conditioned pain ...