Shaped by thousands of years of evolution, the body’s immune system is a vigilant guardian primed against external infectious threats. Too much vigilance, however, and this guardian of potent cells ...

Jacqueline Tabler discusses the role of connective tissues, highlighting the complex relationship between genetics, ...

Extra X chromosomes significantly increase the risk for systemic lupus erythematosus (SLE) and Sjögren disease, with the prevalence of these conditions being higher among patients with Klinefelter and ...

Conventional investigations of the genetic contributors to Alzheimer's disease (AD) risk and progression have ignored the role of the X-chromosome, primarily due to technical analysis limitations. To ...

Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

The 23 pairs of human chromosomes. People who inherit two tall X chromosomes (bottom right) are much more susceptible to autoimmune diseases than people with one X and one short Y chromosome. BSIP / ...

Some people inherit genetic changes that put them at higher risk of developing certain cancers or heart disease. A simple ...

Women age differently from men when it comes to health—particularly in conditions like cardiovascular disease and neurodegenerative disorders such as dementia and Parkinson's. Unlike men, who carry ...

This article is authored by Venkataswamy Eswarachari, associate vice president and senior director, Lab Operations, MedGenome ...

Sensing that breast cancer ran in certain families, the geneticist Mary-Claire King and a team of researchers at UC Berkeley ...