In a recent study posted to the bioRxiv* pre-print server, researchers investigated the complement component 1q (C1q) binding and subsequent complement activation by neutralizing antibodies (nAbs) ...

Serum antibodies to Neisseria meningitidis group B (MenB) polysaccharide are reported not to elicit bacteriolysis in the presence of human complement. To reexamine this question, we evaluated the ...

Researchers identified several antibodies to the nucleocapsid protein from a convalescent COVID-19 patient. Tests found some can inhibit complement hyperactivation and could potentially lead to new ...

argenx and Broteio Pharma have partnered to develop a therapeutic antibody against a complement cascade target through to preclinical proof of concept. The firms say the antibody has the potential to ...

Activation of the complement system through the alternative pathway is necessary for the development of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in animal models C5a has ...

Reviews of Infectious Diseases, Vol. 5, Supplement 4. Bacterial Virulence and Pathogenicity (Sep. - Oct., 1983), pp. S797-S805 (9 pages) An experimental model of pneumococcal bacteremia in guinea pigs ...

THE report with Weller, in 1962, of microcephaly in 14 of 17 infants with generalized cytomegalic inclusion disease established the association of this Central-nervous-system defect with intrauterine ...

CLEVELAND, Sept. 25, 2013 /PRNewswire-USNewswire/ -- Today NovelMed Therapeutics announced preclinical study results for its lead compound in two models of AMD, a major cause of blindness affecting ...

PREVIOUS reports from this Laboratory 1–3 have shown that human growth hormone (HGH) and sheep interstitial cell stimulating hormone (ICSH) produce, in rabbits, precipitin antibodies that are specific ...

ROCKVILLE, Md. and SUZHOU, China, Nov. 5, 2023 /PRNewswire/ -- Innovent Biologics, Inc. ("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and ...