Neurodevelopmental disorders (NDDs) encompass a spectrum of conditions characterised by early-onset cognitive, social and behavioural challenges. Among these, autism spectrum disorder (ASD) and ...

Investigators led by Northwestern Medicine scientists have identified mutations in a gene coding for a key ion channel in the brain as a new cause of a debilitating form of migraine, according to a ...

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of ...

Researchers from the Epilepsy Neurogenetics Initiative (ENGIN) at Children's Hospital of Philadelphia (CHOP) have completed a comprehensive natural history study of SCN8A-related disorders, which ...

Scientists elucidate, for the first time, the structure of the GABA transporter 1 (GAT-1) protein using cryogenic electron microscopy. The findings could lead to new, better treatments for ...

The ketogenic diet (KD) is a high-fat, low-carbohydrate nutritional intervention that shifts systemic metabolism toward ketone body production, offering a ...

It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children. A study ...

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our ...

Genomic analysis of specific and shared causal variants between bipolar disorder I (BD-I) and epilepsy. (A) Venn plot shows the number of specific and shared causal variants between BD-I and epilepsy.