The major inhibitory amino acid transmitter within the mammalian central nervous system (CNS) is GABA. Largely all of the brain’s neurons respond to GABA, while approximately 20% use it as their ...

A three-dimensional structure of the type A GABA receptor bound with GABA and propofol embedded in a cell membrane. Propofol is the most commonly used intravenous anesthetic and acts through the ...

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for ...

Axsome obtains exclusive global rights to AZD7325, a novel oral selective GABAA α2,3 receptor positive allosteric modulatorDeepens Axsome’s broad ...

Using a state-of-the-art method, researchers have succeeded for the first time at unraveling the effects of autoimmune antibodies, that are directed against the brain, in detail at the atomic level.

Scientists at Jiangsu Hengrui Pharmaceuticals Co. Ltd., Shanghai Senhui Pharmaceutical Co. Ltd. and Shanghai Shengdi Pharmaceutical Co. Ltd. have described benzene ring derivatives acting as GABA-A ...

Glen Rock, N.J., March 04, 2020 (GLOBE NEWSWIRE) -- RespireRx Pharmaceuticals Inc. (OTCQB: RSPI) (“RespireRx” or the “Company”), a leader in the research and development of ampakines for a variety of ...

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas ...

Tweaking the numbers of receptors in a key brain area changes the daily rhythms of rest and wake in mice. In humans and other animals, signals from a central circadian clock in the brain generate the ...

Medically reviewed by Karina Tolentino, RD GABA may help manage depression by increasing levels in your brain. Some evidence suggests GABA may improve sleep by having a sedative effect. You may safely ...