From the first unzip of the double helix to the final joining of DNA fragments, replication is a carefully coordinated process. Understanding it helps explain how life preserves its genetic code with ...

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

Inhibiting RNase H2 increases DNA damage and activates immune responses in triple-negative breast cancer, suggesting a dual-action strategy that enhances existing therapies, improves tumor targeting, ...