Chromatography is the science of separating molecules of interest to identify, quantify or even purify them. Properties of the target molecules such as their solubility, size or hydrophobicity give ...

Follow the LCGC Interview series this week to celebrate 50 years of ion chromatography with individual interviews with ...

Cation- and anion-exchange chromatography columns are used routinely for the downstream processing of therapeutic antibodies and proteins. Despite their frequent use, they are considered less ...

The term liquid chromatography (LC) refers to a class of physicochemical methods which are used to separate and quantify compounds in a sample. LC is made up of a liquid mobile phase, which carries ...

Rising drug costs have increased public pressure on the biopharmaceutical industry to find ways to identify and eliminate high-cost unit operations. Biopharmaceutical manufacturing groups now ...

IN the technique of ion-exchange chromatography, the order in which compounds are eluted from a column depends basically upon differences in their ionization constants; but other factors modify and in ...

In this paper, the authors introduce a method that combines ion exchange chromatography with an easier-to-perform, simpler one-step post-column derivatization that is selective to nitrite and visible ...

When ion-exchange chromatography and mass spectrometry are coupled using electrochemical ion suppression, it allows for the selective and specific analysis of highly polar and ionic compounds. The ...

THE importance of many carboxylic acids in metabolism makes it desirable that techniques for their estimation should, in general, be applicable to extracts of plant and animal tissues. It is essential ...

What makes sugar analysis difficult? The sensory and textural properties of foods can be attributed to monosaccharides, such as glucose, fructose, sucrose, and oligo and polysaccharides. The main ...