Scientists have long wanted to get a closer look at the movement of lipids around a cell, but because organelles are so close ...

Lipids are fatty molecules that play critical roles in cell function, including membrane structure, energy storage and ...

The TMEM16 family of membrane proteins was hailed as representing the elusive calcium-activated chloride channels. However, the majority of the family members turned out to be scramblases, proteins ...

Lipids and membrane proteins existing in cell membranes, which locates at the outermost layer of cells, are responsible for recognizing extracellular environments and transferring that information ...

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, adjusting the permeability of the membrane can improve drug delivery. Adding ...

A computer-driven strategy has revealed new insights into how membrane proteins behave and function, potentially aiding drug and therapeutic design.

Multidrug resistance (MDR) is a major obstacle in cancer therapy. It results from different mechanisms; among them is P-glycoprotein (P-gp)-mediated drug efflux out of cells. The mechanism of action ...

A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Assembly and budding of a virus from a membrane microdomain. Viruses have an outer protein shell called a capsid which surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an ...

Max Planck Institute of Molecular Cell Biology and Genetics led a study showing that directional, non-vesicular lipid transport drives fast, species-selective lipid sorting, outpacing slower, less ...