The Colts look to avoid back-to-back losses for the first time when they go to Olympiastadion in Berlin, Germany. Indianapolis dropped its second game of the season against Pittsburgh, 27-20, while Atlanta lost a nail biter to New England, 24-23.

A 17-year veteran quarterback is the new favorite to win NFL MVP, according to the latest betting odds. Here's a full look:

Before digesting the power rankings, let’s check in with the latest ESPN playoff odds for the Bills in four key metrics. Buffalo is headed in the wrong direction again. This, after reclaiming the top spot in Week 10. Now? They’re down to four, behind the Indianapolis Colts, New England Patriots, and Denver Broncos. Not great.

Here is how Pro Football Focus ranks all 32 NFL offensive lines heading into Sunday of Week 10 of the 2025 NFL season.

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Sam Farmer makes his picks and predictions for Week 11 of the NFL season, with the Rams defeating the Seattle Seahawks in an NFC West showdown at SoFi Stadium.

The top of the AFC North standings became a closer race after week 10 of the NFL season, with the Ravens winning their third straight game, the Steelers losing in prime time, and the Bengals having a bye week.

The Bills’ odds haven’t taken a huge hit for Week 11, despite facing a marquee matchup against the Tampa Bay Buccaneers. The Bills are 5.5-point favorites. Tampa Bay and Buffalo have both lost a bit of shine in the last week (TB lost to the Patriots in the Tom Brady Former Teams Bowl), but could easily right the ship with a win here.