DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...
Osaka, Japan--Amines are vital in nature; for example, amino acids -- the building blocks of proteins and thus fundamental to life -- are amines. Numerous materials including pharmaceuticals, dyes, ...
A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...