The combination of preoperative opioid use and depression increased postsurgical risk for chronic postsurgical pain and persistent opioid use.

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows. The study, "Prescription Opioid Duration, Dose, and ...

A nurse fills a syringe of the Johnson & Johnson single dose vaccine during a walk-up clinic on May 6, 2021, in D.C. (Amanda Voisard/For The Washington Post) Lee Hockstader’s May 22 online column, ...

Patients who increased doses of opioid medicines to manage chronic pain were more likely to experience an increase in depression, according to Saint Louis University findings in Pain. The study, ...

Ingesting just one oxycodone tablet and moderately consuming alcohol can increase the risk of respiratory depression, a potentially fatal side effect caused by drug overdose, according to a new study ...

Donald Trump has signed an executive order to accelerate access to medical research and treatments involving psychedelic ...

The search for a safer opioid has followed pain medicine for decades. Doctors still need strong drugs for surgery, major ...

Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications. However, the brain mechanisms important for these rapid treatment ...

Chronic opioid therapy is often misunderstood as primarily producing euphoria, even in long-term pain patients. In reality, ...

Studies show that ibogaine can be effective for short-term opioid addiction treatment, especially reducing drug cravings and some withdrawal symptoms.