PIP2 is an important phosphoinositide that is present in around 1% of the plasma membrane. It is also involved in signal transduction of intracellular and extracellular components. There are two ...
Perhaps no topic is hotter in Alzheimer disease molecular research today than the synaptic effects of amyloid-β (Aβ) oligomers. These toxic assemblies disrupt synaptic function, and are leading ...
No living cell, to paraphrase John Donne, is an island. Even cells that qualify as complete organisms—unicellular organisms—can benefit from interactions with other cells. And mutual dependence is ...
The phosphoinositide 3-kinase (PI3K) signalling cascade occupies a central role in the regulation of cell growth, survival and metabolism, and its dysregulation represents one of the most frequent ...
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