Primary amines and secondary imines are key intermediates widely used in fields like food additives, pharmaceuticals, and agrochemicals. They can be produced via the reductive amination of carbonyl ...

The geometric isolation of metal species in single-atom catalysis (SACs) not only maximizes the atomic utilization efficiency, but also endows SACs with unique selectivity in various transformations.

This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...