Rheumatoid arthritis is a long-term autoimmune disease in which the immune system mistakenly attacks healthy joints. This ...

A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the ...

Affecting more than 2 million Americans, rheumatoid arthritis (RA) remains an enigma. The chronic swelling and pain brought about by RA can be debilitating in severe cases, and, as is true of most ...

A plant-derived compound reduced swelling, inflammation, and joint damage in rats with rheumatoid arthritis. It also helped rebalance immune activity and improve the way certain fats were processed in ...

Since the concept of "gut-joint" axis was proposed, increasing evidence has shown that the imbalance of gut microbiota may play a key role in the occurrence and development of rheumatoid arthritis (RA ...

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), ...

LIVERPOOL, ENGLAND — The IRIS-RA study of the investigational monoclonal antibody drug nipocalimab in patients with rheumatoid arthritis (RA) did not meet its primary endpoint, but there could still ...

New research findings published in the Journal of Leukocyte Biology, suggest that synovial CD4+ T cells that produce IL-21 contribute to joint inflammation by activating synovial fibroblasts in ...

C-T-P, compound-target-pathway; DL, drug-likeness; GO, gene ontology; OB, oral bioavailability; PPI, protein-protein interaction; RA, rheumatoid arthritis; TCMSP ...