Addressing a critical technical limitation in multi-cycle imaging - the reliable adhesion and retention of suspension-derived ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...

Fibroblasts are crucial cells for shaping tissue architecture and immune cell niches 1,2,3. Studying the heterogeneity of fibroblast subtypes has been challenging due to the scarcity of unique surface ...

When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a ...

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

A new computational method could dramatically accelerate efforts to map the body's cells in space, according to a study published in Nature Genetics. Spatial multi-omics technologies—often described ...

MSK immunologist Dr. Andrea Schietinger and colleagues found that a 'triad' of immune cells is required to kill cancer cells. The discovery could alter the way doctors administer immunotherapies.