Biology and medical researchers use spatial transcriptomics (ST) technologies to detect transcription levels in cells, predict cell types and build a tissue's three-dimensional (3D) structure. However ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Spatial transcriptomics may have just achieved single-cell resolution. Researchers led by Evan Macosko, Fei Chen, and colleagues at the Broad Institute in Cambridge, Massachusetts, bound together ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Researchers have developed Fullscope-seq, a long-read spatial transcriptomics platform that maps alternative transcript isoforms within intact tissues at single-cell resolution - opening new ...

A Vanderbilt Health and TGen team applied spatial transcriptomics to heart transplant biopsies, uncovering cellular programs linked to rejection, therapy response, and cardiac allograft vasculopathy.

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...