Background Significant trauma and muscular tightness often result during Total Knee Artroplasty (TKA) surgery and thus act to restrict tissue fluid movement resulting with lower extremity oedema.

Correspondence to Dr Laura C Cappelli, Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA; lcappel1{at}jhmi.edu Objective We sought to investigate the long-term outcomes of ...

Background A new autoinflammatory syndrome related to somatic mutations of UBA1 was recently described and called VEXAS syndrome. Objectives To describe clinical characteristics, laboratory findings ...

Background Vitamin D is important for bone, cartilage and muscle function but there are few studies on its association with joint pain. Objective To investigate whether serum vitamin D predicts change ...

Background Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is an acute inflammatory polyartritis and palpable pitting edema of the elderly patients. It dramatically ...

Pathology Department, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium Correspondence to Professor F A Houssiau, Rheumatology Department, Cliniques ...

Objectives To compare the use of glucocorticoids (GC) over time in patients with rheumatoid arthritis (RA) who were or were not treated initially with GC bridging therapy. Methods Data from the BeSt, ...

1 Flinders University Department of Rehabilitation and Aged Care, Repatriation General Hospital, South Australia 2 Physiotherapy Department, Repatriation General Hospital, South Australia ...

Background Rituximab (RTX) is the most commonly used biologic for the treatment of SLE. However, there is are no clinically applicable predictors of response, which is of particular importance in this ...

Correspondence to Professor Masaaki Murakami, Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan; ...

1 Faculty of Health Sciences, University of Sydney, Lidcombe, New South Wales, Australia 2 Graduate School of Medicine, Notre Dame University, Darlinghurst, New South Wales, Australia 3 Covance Pty ...

Background: Macrophage activation plays a crucial part in synovial inflammation, a driving force in osteoarthritis (OA) [1]. Our previous research has revealed that NOD2 attenuates OA by modulating ...