As Professor Davies explains, the successful application of 3Rs initiatives across the UK means there is now far more information to capture. Presenting a detailed breakdown of reductions in the most ...

EMA Updates on 3Rs Guideline Review The European Medicines Agency (EMA) on Tuesday published a report on actions taken to update its guidelines following a review of 3Rs, or replacement, reduction and ...

Using animals for research raises ethical concerns that are addressed in project evaluation by weighing expected harm to animals against expected benefit to society. A harm–benefit analysis (HBA) ...

The term 'compliance' describes behaviors or actions that are in accordance with regulations or standards 1. In research using animals, written standard operating procedures and good laboratory ...