The maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) remains a major challenge in developing functional in vitro cardiac models. While three-dimensional (3D) culture systems ...
Background: Lamin A/C (LMNA) is a nuclear intermediate filament protein that is expressed ubiquitously. LMNA mutations account for 6% of dilated cardiomyopathy, and patients affected by these ...
Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis. (S.P., J.H.S., K.R.S., U.O., M.K.S., F.F., H.C.V., E.S.C., J.C.L.) Department ...