For Week 18 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 18 NFL schedule here. After analyzing every game in Week 18, the AI says the Rams (-7.5, 46.5), who have already clinched a postseason berth, cover comfortably against the Cardinals.

Two win-or-go-home games. Two games to decide the AFC South champs. And a Seahawks-49ers game will determine the NFC's top seed. Nice.

Frank Ammirante's five fantasy football bold predictions for Week 17 of the 2025 NFL season. Expert predictions for Trevor Lawrence, Ashton Jeanty, Rhamondre Stevenson, Brian Thomas Jr, and Juwan Johnson.

This is it, football fan! The final week of the 2025-26 NFL regular season has arrived. Two games will take place on Saturday, another 14 will be played on Sunday, and that two-day stretch will put the finishing touches on this year's playoff field.

The Detroit Lions will look to close out their season with a win against the Chicago Bears on Sunday. The Bears have already clinched an NFC North championship.

Mike Florio and Chris Simms explain why they think the Rams will be motivated by their Week 17 loss to the Falcons, and will close out the regular season strong with a win against the Cardinals.

The Seahawks will play their most important game of the season in Week 18. Here are 3 Seahawks bold predictions against the 49ers.

The Carolina Panthers and Tampa Bay Buccaneers are playing one of the most important matchups of Week 18. The NFL regular season will conclude after, but not be