Houston held Christian McCaffrey to 68 yards with a plan that started up front and also included the Texans' offense.

When the San Francisco 49ers finally picked up a first down Sunday against the Houston Texans they were already down by 16 points and there was less than a minute left in the first half.

The San Francisco 49ers entered their Week 8 matchup against the Houston Texans as favorites and lost. Here were the worst performers from the loss.

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has given no reason to believe it can be effective. The Texans' defense will keep them in this game for a bit but it can only do so much, as we saw Monday in Seattle.

PUNT RETURNS_San Francisco, None. Houston, Noel 2-11. KICKOFF RETURNS_San Francisco, B.Robinson 3-99, Moore 2-52. Houston, Pierce 3-70.

Preview the New England Patriots' NFL week 9 matchup with the Falcons, including betting odds, tips, trends, and game information.