Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

The Houston Texans have a critical home matchup on the horizon against the San Francisco 49ers following a less-than-ideal ...

Find out how to watch the NFL Week 8 game between the Houston Texans and San Francisco 49ers, as well as the latest odds and ...

The San Francisco 49ers (5-2) visit the Houston Texans (2-4) Sunday in Week 8. Kickoff from NRG Stadium in Houston, Texas, is ...

Preview the Week 8 matchup between the Houston Texans and San Francisco 49ers with predictions, odds, over/under, spread, ...

Looking for a best bet for Sunday’s NFL action? You’ve come to the right place, as the SI Betting team has been making ...

The San Francisco 49ers will take on the Houston Texans in Week 8. Here's what the experts think will happen on Sunday ...

Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the ...

Get a prediction, pick and odds for the NFL Week 8 matchup between the Houston Texans and the San Francisco 49ers.

Our expert Week 8 NFL predictions expect the 49ers to cover the spread behind All-Pro running back Christian McCaffrey!

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has ...