A new quantum computing protocol may be able to augment a standard technique for understanding molecules in chemistry, ...

What happens when you squeeze DNA? Can pressure reveal something about how our genetic material is packed, protected, and ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.

The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can transform H3.3 nucleosomes from a stable state to a dynamically activated ...

If we can fully map the structure of our brains, will we be able to understand how they work? That is the goal of researchers attempting to build a wiring diagram, or connectome, of our neural ...

Your brain ventricles are four fluid-filled chambers that produce cerebrospinal fluid. This fluid helps nourish your brain and protect it from injury. It would be easy to argue that your brain is the ...

The development of many psychiatric disorders, including depression, schizophrenia and bipolar disorder, is known to be in great part influenced by genetics. Past research has identified various genes ...

Copyright (C) 2024 Xiao Wang, Yuanyuan Zhang, Suhita Ray, Anupama Jha, Tangqi Fang, Shengqi Hang, Sergei Doulatov, William Stafford Noble, and Sheng Wang License ...

ABSTRACT: Background: The emerging evidence of the global decline in sperm counts worldwide has intensified concerns about male infertility. This widespread interest is increasingly accentuated in sub ...

Thanks in advance for your help and for this very useful new command added to modkit. I'm using modkit open-chromatin predict on modBAMs generated with 6mA calls from EcoGII labelled gDNA, using ...

Histone variants are specialized isoforms of histone proteins that play crucial roles in regulating chromatin structure and function, influencing transcription, DNA repair, and cell cycle progression.

Request permissions for this article. Laboratory of Chromatin Structure and Function, Institute for Quantitative BiosciencesThe University of Tokyo 1-1-1 Yayoi, Bunkyo-ku Tokyo 113-0032 Japan ...