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Statistical principles in neurointervention part 2. Multivariable analysis: generalized linear models, modification, confounding, and mediation

Neurointervention is a highly specialized area of medicine and, as such, neurointerventional research studies are often more challenging to conduct, require large, multicenter efforts and longer study ...
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Middle meningeal artery embolization as a surgical adjunct for non-acute subdural hematoma: real world outcomes and treatment effect heterogeneity

Background Middle meningeal artery embolization (MMAE) is a promising treatment for non-acute subdural hematoma (NASDH), but trial evidence is limited by heterogeneity and open label design bias. This ...
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Design limitations and unintended consequences of the AHRQ patient safety indicator for endovascular thrombectomy stroke care

Background To monitor endovascular and surgical care quality, the US Agency of Healthcare Research and Quality (AHRQ) has established a “failure-to-rescue” safety metric - Patient Safety Indicator ...
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Endovascular repair of direct carotid–cavernous fistula in Ehlers–Danlos type IV

Ehlers–Danlos syndrome (EDS) type IV is a collagen vascular disease with an autosomal dominant inheritance caused by COL3A1 mutation. Patients with EDS type IV can present with organ rupture, ...
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Safety and efficacy of selective and superselective intra-arterial cerebral infusion with blood–brain barrier disruption for glioma: a systematic review and meta-analysis

Background Selective and superselective intra-arterial cerebral infusion (SIACI/SSIACI) delivers chemotherapy directly to tumor-supplying arteries, achieving high local drug levels with reduced ...
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Subclavian loop catheterization technique (SLOT): novel transradial salvage technique for challenging vertebral artery ostial stenosis

Objective To evaluate the efficacy and safety of the subclavian loop catheter technique for endovascular stenting of vertebral artery ostial stenosis (VAOS). Methods We retrospectively reviewed all ...
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Blebs in intracranial aneurysms: prevalence and general characteristics

Correspondence to Seyedeh Fatemeh Salimi Ashkezari, Department of Bioengineering, George Mason University, Fairfax, VA 22030, USA; ssalimia{at}gmu.edu Background Blebs are rupture risk factors in ...
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Safety and efficacy of stent-assisted coiling with the pEGASUS-HPC stent in wide-necked intracranial aneurysms: a multicenter retrospective analysis

7 Central Institute for Diagnostic and Interventional Radiology Neuroradiology and Nuclear Medicine, Offenbach am Main, Germany 8 Institute for Diagnostic and Interventional Radiology and ...
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Acute thrombus formation on phosphorilcholine surface modified flow diverters

Correspondence to Dr Matthew J Gounis, Department of Radiology Director, New England Center for Stroke Research University of Massachusetts, 55 Lake Ave N, SA-107R, Worcester, MA 01655, USA; ...
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Comparison between contact aspiration alone and combined thrombectomy for intracranial internal carotid artery occlusion: insights from SARA-3 registry

Background Acute intracranial internal carotid artery (ICA) occlusion lowers first-pass reperfusion rates and clinical outcomes. Aspiration catheter and stent-retriever thrombectomy (CA+SR) is ...
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Cerebrovascular geometry in the anterior circulation: an analysis of diameter, length and the vessel taper

1 Department of Interventional Neuroradiology, West Virginia University Hospital, Morgantown, West Virginia, USA 2 Department of Community Medicine and Biostatistics, West Virginia University Hospital ...
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Intra-arterial human serum albumin therapy following mechanical thrombectomy for acute ischemic stroke: the AMASS pilot trial

Background Despite successful mechanical thrombectomy (MT), approximately 50% of patients with large vessel occlusion (LVO) stroke experience poor outcomes due to reperfusion injury. Intra-arterial ...