Jan 10, 2025 · The successful cultivation of stable CTC-derived organoids has enabled an investigation into methods of survival and resistance in cancer cells. A team of researchers from the German Cancer Research Centre, the Heidelberg Institute for Stem Cell Technology and Experimental Medicine and the ...

Jan 31, 2025 · Explore BioTechniques. A world leader in life science method research news. ISSN (print): 0736-6205 | ISSN (online): 1940-9818.

Jan 6, 2025 · Novel peptide-modified lipid nanoparticles can cross the blood–brain barrier and target neurons, taking one step closer to next-generation treatments for neurological diseases. Researchers at the University of Pennsylvania School of Engineering and Applied Science (PA, USA) have modified lipid ...

Jan 30, 2025 · Tony Oosterveen (left) is a Principal Scientist at bit.bio (Cambridge, UK), a company pioneering the generation of physiologically relevant human cell types from induced pluripotent stem cells (iPSCs) with its deterministic, cell programming opti-ox technology. Tony leads a team focused on ...

Jan 6, 2025 · Legacy sequencing technologies have, undoubtedly, made comprehensive transcriptome analysis possible and are invaluable for the study of human genetics and mechanisms of diseases. However, legacy technologies struggle to generate full-length transcripts, require fragmentation and rely on converting RNA to cDNA. In this white paper, find out how nanopore sequencing overcomes these limitations ...

Jan 24, 2025 · In this interview feature, we catch up with our Editor-in-Chief, Michelle Itano (University of North Carolina at Chapel Hill, NC, USA) to discuss her recent experiences at the annual meeting of the American Society for Cell Biology (ASCB; 14–18 December 2024; CA, USA).Read on for an insight into the key trends at the conference, the developments empowering the investigation of inter ...

Jan 22, 2025 · The recent study consisted of two parts. The first step was to isolate P. alcaligenes from a water sample taken from Medano hot spring.Next, the bacterium’s genomic DNA was sequenced using Oxford Nanopore’s single molecule real-time sequencing technology and then experiments were conducted to determine EPS production at a high temperature to confirm its thermotolerance.

Oct 8, 2024 · The Nobel Prize for Physiology or Medicine has been awarded to Victor Ambros (University of Massachusetts Medical School) and Gary Ruvkun (Harvard Medical School [HMS], both MA, USA) for their discovery of microRNA – small, non-coding RNA molecules – and its role in gene regulation.Revealing new layers of genome regulation. Since their discovery in the 1960s, transcription factors have ...

Jan 24, 2025 · NIH reviews, travel and communications have been frozen until 2 February at least. How has the scientific community responded? On day three of Trump’s presidency, the administration imposed a wide range of restrictions on the National Institutes of Health (NIH; MD, USA), including canceling research-grant reviews, travel, training, meetings and communications.

Sep 26, 2024 · To address this, researchers at the University of North Carolina at Chapel Hill (NC, USA) carried out TPA whole-genome sequencing on samples from people with syphilis from four countries: Colombia, China, Malawi and the US.. The researchers analyzed the resulting data, compared it to publicly available data and mapped mutations to 3D …