Does Grapefruit Affect Medication - Search Videos

How Grapefruit Affects Drug Metabolism | The CYP3A4 Interaction explained

YouTubeProfessor G - Pharmacology

How Grapefruit Affects Drug Metabolism | The CYP3A4 Interaction explained

Grapefruit–drug interactions are one of the most well-established and clinically relevant food–drug interactions in pharmacology. In this short lecture, we explore how grapefruit juice alters drug metabolism, why the interaction was discovered by chance, and how inhibition of intestinal CYP3A4 leads to increased drug exposure. Using ...

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